Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics. Santos M, Niemi M, Hiratsuka M, Kumondai M, Ingelman-Sundberg M, Lauschke VM, Rodríguez-Antona C. Genet Med. 2018 Jun;20(6):622-629.

Posted on May 15, 2019 by Wendy van Hemmen

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Medical education in pharmacogenomics-results from a survey on pharmacogenetic knowledge in healthcare professionals within the European pharmacogenomics clinical implementation project U-PGx. Just KS, Steffens M, Swen JJ, Patrinos GP, Guchelaar HJ, Stingl JC. Eur J Clin Pharmacol. 2017 Oct;73(10):1247-1252.

Posted on May 15, 2019May 15, 2019 by Wendy van Hemmen

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Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients. Chondrou V, et al., Katsila T, Patrinos GP. Hum Genomics. 2017 Oct 23;11(1):24.

Posted on May 15, 2019May 15, 2019 by Wendy van Hemmen

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Clinical Pharmacogenetics Implementation Consortium (CPIC) Meeting June 6-7, 2019

Posted on February 7, 2019February 7, 2019 by Wendy van Hemmen

The Clinical Pharmacogenetics Implementation Consortium (CPIC®) Meeting will be held in Memphis, TN at St. Jude Children’s Research Hospital on June 6th (full day) and June 7th (1/2 day). CPE and CME will be offered. Information, including registration and hotel information, is available here. Continue reading →

Happy cross-over day!

Posted on October 4, 2018December 13, 2018 by Wendy van Hemmen

On October 1^st 2018, the PREPARE study sites have crossed-over to the opposite arm! Sites in Spain, Greece and Slovenia have been enrolling patients for the pharmacogenomics guided prescribing arm Continue reading →

Dutch pharmacogenomics guidelines endorsed in Europe

Posted on September 25, 2018December 13, 2018 by Wendy van Hemmen

Six European heathcare organisations, including the European Association of Clinical Pharmacology & Therapeutics (EACPT) and the European Association of Hospital Pharmacists (EAHP), now have endorsed the pharmacogenomic guidelines used in U-PGx. Continue reading →

PharmGKB Demo at U-PGx Summer School

Posted on August 27, 2018August 27, 2018 by Wendy van Hemmen

PharmGKB recently held a demonstration of the PharmGKB website as part of the U-PGx Summer School in Bonn, Germany. Continue reading →

Leiden team included 100% of original target!

Posted on July 18, 2018December 19, 2018 by Wendy van Hemmen

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First 2,500 patients enrolled!

Posted on May 3, 2018May 3, 2018 by Wendy van Hemmen

The PREPARE study team is proud to announce that the first 2,500 patients have been enrolled for the PREPARE study! Continue reading →

Pitfalls and Opportunities for Epigenomic Analyses Focused on Disease Diagnosis, Prognosis, and Therapy. Lauschke VM, Ivanov M, Ingelman-Sundberg M. Trends Pharmacol Sci. 2017 Sep;38(9):765-770.

Posted on April 24, 2018May 14, 2019 by Wendy van Hemmen

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