Ubiquitous Pharmacogenomics (U-PGx)
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Publications

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients. Jukić MM, Haslemo T, Molden E, Ingelman-Sundberg M. Am J Psychiatry. 2018 May 1;175(5):463-470.

Posted on May 15, 2019 by Wendy van Hemmen

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Pharmacoepigenetics and Toxicoepigenetics: Novel Mechanistic Insights and Therapeutic Opportunities. Lauschke VM, Barragan I, Ingelman-Sundberg M. Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:161-185.

Posted on May 15, 2019 by Wendy van Hemmen

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Identification of approved drugs as potent inhibitors of pregnane X receptor activation with differential receptor interaction profiles. Burk O, Kuzikov M, Kronenberger T, Jeske J, Keminer O, Thasler WE, Schwab M, Wrenger C, Windshügel B. Arch Toxicol. 2018 Apr;92(4):1435-1451.

Posted on May 15, 2019 by Wendy van Hemmen

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Validation of a high-performance liquid chromatography method for thiopurine S-methyltransferase activity in whole blood using 6-mercaptopurine as substrate. Rieger H, Schmidt P, Schaeffeler E, Abe M, Schiffhauer M, Schwab M, von Ahsen N, Zurek G, Kirchherr H, Shipkova M, Wieland E. Clin Chem Lab Med. 2018 Apr 25;56(5):803-809.

Posted on May 15, 2019 by Wendy van Hemmen

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Population pharmacogenomics: impact on public health and drug development. Patrinos GP. Pharmacogenomics. 2018 Jan;19(1):3-6.

Posted on May 15, 2019May 15, 2019 by Wendy van Hemmen

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Genomic variants in the FTO gene are associated with sporadic amyotrophic lateral sclerosis in Greek patients. Mitropoulos K, et al., Katsila T, Patrinos GP. Hum Genomics. 2017 Dec 8;11(1):30.

Posted on May 15, 2019 by Wendy van Hemmen

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Genetic variation in human drug-related genes. Schärfe CPI, Tremmel R, Schwab M, Kohlbacher O, Marks DS. Genome Med. 2017 Dec 22;9(1):117. doi: 10.1186/s13073-017-0502-5.

Posted on May 15, 2019 by Wendy van Hemmen

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Pharmacogenomic Biomarkers for Improved Drug Therapy-Recent Progress and Future Developments. Lauschke VM, Milani L, Ingelman-Sundberg M. AAPS J. 2017 Nov 27;20(1):4.

Posted on May 15, 2019 by Wendy van Hemmen

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Measuring the Value of Pharmacogenomics Evidence. Patrinos GP, Mitropoulou C. Clin Pharmacol Ther. 2017 Nov;102(5):739-741.

Posted on May 15, 2019May 15, 2019 by Wendy van Hemmen

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Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics. Santos M, Niemi M, Hiratsuka M, Kumondai M, Ingelman-Sundberg M, Lauschke VM, Rodríguez-Antona C. Genet Med. 2018 Jun;20(6):622-629.

Posted on May 15, 2019 by Wendy van Hemmen

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Recent Posts

  • Matching medication to DNA leads to 30% fewer side effects
  • U-PGx Personalized Medicine Symposium
  • bio.logis receives the E-Health Award Hessen 2021
  • 7th U-PGx Personalized Medicine Day
  • Dr. Cristina Lucía Dávila Fajardo obtains PhD degree in pharmacogenetics
This project has received funding from the European Union's Horizon 2020 research and innovation programme under grant agreement No 668353.