The tyrosine kinase inhibitor sunitinib is used as first-line therapy in patients with metastasized renal cell carcinoma (mRCC), given in fixed-dose regimens despite its high variability in pharmacokinetics (PKs). Interindividual variability of drug exposure may be responsible for differences in response. Therefore, dosing strategies based on pharmacokinetic/pharmacodynamic (PK/PD) models may be useful to optimize treatment. Continue reading
The 3rd UPGx Personalized Medicine Day will be organized in Toulouse, France. The meeting will be co-organized by the Golden Helix Foundation and the University of Toulouse, both partners of the Ubiquitous Pharmacogenomics (UPGx) project, funded by the European Commission (H2020-668353). Continue reading
On July 21st, 2017, H.E. the United States Ambassador to Greece Mr. Geoffrey Pyatt visited the Laboratory of Molecular Biology and Immunology, University of Patras (UPAT), as part of his visit to academic entities in Patras that produce and offer innovative results and services in the biotechnology and healthcare sectors.
The 2nd UPGx Personalized Medicine Day will be organized in Vienna, Austria on Friday May 12th, 2017. The meeting will be organized at the Medical University of Vienna and will follow the 2nd Consortium Meeting of the UPGx project that will be held May 10-11, 2017. Continue reading
Despite scientific and clinical advances in the field of pharmacogenomics (PGx), application into routine care remains limited. Opportunely, several implementation studies and programmes have been initiated over recent years. This article presents an overview of these studies and identifies current research gaps. Continue reading
The 1st UPGx Personalized Medicine Day, the first of a series of dissemination events for healthcare professionals and biomedical scientists that will be organized by the UPGx project, has been successfully held on Thursday December 1st, 2016 in Granada, Spain. Continue reading
The 2016 Golden Helix Summer School with the theme “Cancer Genomics and Individualized Therapy” was successfully organized at the Dolphin Bay Resort hotel in Syros island, Greece, 22-26 September 2016. Continue reading
This U-PGx video visualises and promotes the idea of personalised medicine and pre-emptive PGx testing. The video can be be used to inform the public via the webpage, for educational purpose and for communication with stakeholders and at (inter)national workshops. Continue reading